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Pathology Laboratory Services Catalog

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  Test Name
Lyme Disease CSF, Western Blot (IgG and IgM)
Synonyms
LymeWBCSF
Order Includes
Lyme IgG P93 Ab, CSF
Lyme IgG P66 Ab, CSF
Lyme IgG P58 Ab, CSF
Lyme IgG P45 Ab, CSF
Lyme IgG P41 Ab, CSF
Lyme IgG P39 Ab, CSF
Lyme IgG P30 Ab, CSF
Lyme IgG P28 Ab, CSF
Lyme IgG P23 Ab, CSF
Lyme IgG P18 Ab, CSF
Lyme IgM P41 Ab, CSF
Lyme IgM P39 Ab, CSF
Lyme IgM P23 Ab, CSF
Lyme IgG Western Blot Interpretation, C
Lyme Ig
Specimen
CSF
Patient/Specimen Preparation
Do not order this CSF Lyme study without first having a serum test performed "Lyme Disease (total and IgM) Reflexed to
WB". A negative serum study is strong evidence against the disease and may preclude the need for the CSF study.
Please contact the following with questions:
Micro/Immuno Pathology Resident (M - F, 8AM - 5PM)
Pathology Resident On-Call (all other times)
By Commonwealth of Virginia Law, all Lyme testing requires the patient to receive written education as worded below.
This information will print automatically at the patient printer. Please deliver to the patient prior to the end of
their visit or stay.
"According to the Centers for Disease Control and Prevention, as of 2011 Lyme disease is the sixth fastest growing
disease in the United States.
Your health care provider has ordered a laboratory test for the presence of Lyme disease for you. Current laboratory
testing for Lyme disease can be problematic and standard laboratory tests often result in false negative and false
positive results. If done too early, you may not have produced enough antibodies to be considered positive because
your immune response requires time to develop antibodies.
If you are tested for Lyme disease, and the results are negative, this does not necessarily mean you do not have Lyme
disease. If you continue to experience symptoms, you should contact your health care provider and inquire about the
appropriateness of retesting or additional treatment."
Container
CSF Tube
Minimum Volume
CSF Tube:1.00 mL
Special Handling
Storage & Transportation Instructions
(MCVH Campus)
Storage & Transportation Instructions
(Remote Locations)
Refrigerate for storage.
Turn Around Time
Varies by Laboratory
Reference Interval

Lyme IgG P93CSF


0 Minutes - 150 Years : Absent

Lyme IgG P66CSF

0 Minutes - 150 Years : Absent

Lyme IgG P58CSF

0 Minutes - 150 Years : Absent

Lyme IgG P45CSF

0 Minutes - 150 Years : Absent

* NOTE: Please call lab for more detailed reference ranges.

Interpretive Information
Lyme IgG WB CSF
Positive: 5 of the following Borrelia-specific bands: P18, 23, 28, 30, 39, 41, 45, 58, 66, and 93.

Negative: No bands or banding patterns which do not meet positive criteria.

An equivocal or positive EIA result followed by a negative Western Blot result is considered NEGATIVE. An equivocal or positive EIA result followed
by a positive Western Blot result is considered POSITIVE. Criteria for positivity are those recommended by CDC/ASTPHLD. p23=Osp C, p41=flagellin.
For Investigational Use Only.
Testing performed by LabCorp of America

Lyme IgM WB CSF
Positive: 2 of the following bands: 23, 39, or 41

Negative: No bands or banding patterns which do not meet positive criteria.

An equivocal or positive EIA result followed by a negative Western Blot result is considered NEGATIVE. An equivocal or positive EIA result followed
by a positive Western Blot result is considered POSITIVE. Criteria for positivity are those recommended by CDC/ASTPHLD. p23=Osp C, p41=flagellin.
For Investigational Use Only.

Performed by LabCorp of America
1447 York Court
Burlington, NC 27215
Phone: 1 800 537 8378

Additional Interpretive Information
For more information see the LabCorp web site at www.labcorp.com.
Critical Values
Methodology
Western blot
Performing Lab
Send Out
CPT Code

86617 X 2 (LYMEWB, CSF-1)This procedure may be considered by Medicare and other carriers as investigational and, therefore, may not be payable as a covered benefit for patients.

Internal Code
OSM 58108